Work faster, save space - Get higher productivity and purity than with comparable batch - with an even smaller SMB .
Reduce your costs - Save up to 90% of the solvent and reduce the solid phase costs up to 80%.
SMB is a method in process chromatography that enables substance mixtures to be continuously separated and extracted in two fractions. Its efficiency is significantly higher than batch chromatography, through better utilization of the column stationary phase.
Although in principle limited to two fraction separations, each partial fraction can be separated into further fractions by repeated use of the SMB process – down to binary substance mixtures.
Typically, the SMB process is used for two component mixtures, like chiral separations or mixtures with a "leading" or a "trailing" key product peak in the chromatogram.
The AZURA® Lab SMB System is optimized for the separation of binary mixtures in gram-scale. As with the AZURA Lab SMB System special emphasis is put on the continuous operation mode and high productivity. The SMB standard configuration consists of four AZURA Assistans ASM 2.2L with seven multiposition valves and four P 4.1S Pumps as well as our user friendly software PurityChrom MCC and the required IT hardware. Referring to the special needs of every separation the SMB system can be freely configured (e.g. closed-loop, open-loop,) and is upgradable (e.g. detector, flow meter). A maximum pressure up to 130 bar with 8 columns is possible. Depending on your application the columns can be heated or cooled to ensure the perfect and most constant separation conditions. It can be chosen between a stainless steel or a bioinert version.
The AZURA Pilot SMB System is optimized for the separation of binary mixtures in gram to kilogram-scale. As with the AZURA Pilot SMB System special emphasis is put on the continuous operation mode and high productivity. The SMB standard configuration consists of four Pump 2.1L and seven multiposition valves integrated into four AZURA Assistans ASM 2.2L. Our user-friendly software PurityChrom® MCC and the required IT hardware are included too. Referring to the special needs of every separation, the SMB system can be freely configured (e.g. closed-loop, open-loop) and is upgradable (e.g. detector, flow meter). A maximum pressure up to 100 bar (eight columns) is possible. Depending on your application the columns can be heated or cooled to ensure the perfect and most constant separation conditions.
